m-Chlorophenylbiguanide hydrochloride

Key Product Details

Product Description

m-Chlorophenylbiguanide hydrochloride is a prototypical potent and selective 5-HT₃ receptor agonist.

Product Specifications for m-Chlorophenylbiguanide hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for m-Chlorophenylbiguanide hydrochloride

The following data is based on the product molecular weight 248.11.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.03 mL	20.15 mL	40.30 mL
5 mM	0.81 mL	4.03 mL	8.06 mL
10 mM	0.40 mL	2.02 mL	4.03 mL
50 mM	0.08 mL	0.40 mL	0.81 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Sepulveda The agonist properties of m-chlorophenylbiguanide and 2-methyl-5-hydroxytryptamine on 5-HT₃ receptors in N1E-115 neuroblastoma cells. Br.J.Pharmacol. 1991 PMID: 1797317
• Kilpatrick 1-(m-Chlorophenyl)biguanide, a potent high affinity 5-HT₃ receptor agonist. Eur.J.Pharmacol. 1990 PMID: 2144822
• Niemeyer and Lummis Different efficacy of specific agonists at 5-HT₃ receptor splice variants: the role of the extra six amino acid segment. Br.J.Pharmacol. 1998 PMID: 9517385
• Boess 5HT₃ receptors in NG108-15 neuroblastoma X glioma cells: effect of the novel agonist 1-(m-chlorophenyl)biguanide. Neuropharmacology 1992 PMID: 1407396

Product Documents for m-Chlorophenylbiguanide hydrochloride