Chemical Name: 1-(3-Chlorophenyl)biguanide hydrochloride
Biological ActivityPrototypical potent and selective 5-HT3 receptor agonist.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
5HT3 receptors in NG108-15 neuroblastoma X glioma cells: effect of the novel agonist 1-(m-chlorophenyl)biguanide.
Boess et al.
1-(m-Chlorophenyl)biguanide, a potent high affinity 5-HT3 receptor agonist.
Kilpatrick et al.
The agonist properties of m-chlorophenylbiguanide and 2-methyl-5-hydroxytryptamine on 5-HT3 receptors in N1E-115 neuroblastoma cells.
Sepulveda et al.
Different efficacy of specific agonists at 5-HT3 receptor splice variants: the role of the extra six amino acid segment.
Niemeyer and Lummis
Citations for m-Chlorophenylbiguanide hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for m-Chlorophenylbiguanide hydrochloride include:
4 Citations: Showing 1 - 4
Vort. disinhibits pyramidal cell function and enhances synaptic plasticity in the rat hippocampus.
Authors: Dale Et al.
J Psychopharmacol 2014;28:891
First and second generation antipsychotics influence hippocampal gamma oscillations by interactions with 5-HT3 and D3 receptors.
Authors: Schulz Et al.
Br J Pharmacol 2012;167:1480
Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.
Authors: Huang Et al.
PLoS One 2009;29:13909
Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells.
Authors: Gill Et al.
Am J Physiol Gastrointest Liver Physiol 2008;295:G700
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