receptor agonist/partial agonist; displays some activity at 5-HT2A
values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT2C
, bovine 5-HT1A
and rat 5-HT1B
receptors respectively. Suppresses locomotor activity in rats in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells.
Porter et al.
m-CPP: a tool for studying behavioural responses associated with 5-HT1C receptors.
Curzon et al.
Effect of 1-(m-Chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity.
Lucki et al.
VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin).
Hoyer et al.
The citations listed below are publications that use Tocris products. Selected citations for m-CPP hydrochloride include:
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