M4K2163 dihydrochloride

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M4K2163 dihydrochloride | ALK/CD246
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Description: Potent and selective ALK2 inhibitor

Chemical Name: 1-[4-[5-(4-Fluoro-3,5-dimethoxyphenyl)-4-methyl-3-pyridinyl]phenyl]piperazine dihydrochloride

Purity: ≥98%

Product Details

Biological Activity

M4K2163 is a potent and selective activin receptor-like kinase 2 (ALK2) inhibitor (IC50 values are 19 nM in vivo and 98 nM in vitro). Orally bioavailable and brain penetrant.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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