M617

Catalog # Availability Size / Price Qty
2697/1
M617
1 Image
Description: Selective GAL1 agonist
Alternative Names: Galanin(1-13)-Gln14-bradykinin(2-9)amide
Product Details
Citations (1)
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Biological Activity

Selective galanin GAL1 receptor agonist (Ki values are 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively). Enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pain.

Technical Data

Formula:
C112H161N29O28
Sequence:
GWTLNSAGYLLGPQPPGFSPFR

(Modifications: Arg-22 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
860790-38-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling.
    Mazarati et al.
    J.Pharmacol.Exp.Ther., 2006;318:700
  2. Activation of peripheral galanin receptors: differential effects on nociception.
    Jimenez-Andrade et al.
    Pharmacol.Biochem.Behav., 2006;85:273
  3. A galanin receptor subtype 1 specific agonist.
    Lundstrom et al.
    Int.J.Pept.Res.Ther., 2005;11:17

Product Datasheets

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Citation for M617

The citations listed below are publications that use Tocris products. Selected citations for M617 include:

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