Mag-Fura-2 AM
Tocris Bioscience | Catalog # 7855
Key Product Details
Description
Wavelength
Product Description
Mag-Fura-2 AM is a cell-permeable fluorescent magnesium ion (Mg2+) indicator. It shows selectivity for Mg2+ over other bivalent ions (Zn2+, Cu2+ and Ca2+). It exhibits >13,000-fold selectivity for Mg2+ ions over Ca2+ ions (Mg2+ Kd = 1.9 nM vs Ca2+ Kd = 25 μM). Excitation and emission maxima (λ) are 369 and 511 nm, respectively. Mag-Fura-2 AM can be used as an indirect indicator of ATP consumption/production.It is recommended to prepare stock solutions in DMSO.
Optical Data
| λabs | 369 nm |
| λem | 511 nm |
| Extinction Coefficient (ε) | 31000 M-1cm-1 |
| Cell Permeable | Yes |
| Application | Confocal Imaging, Flow Cytometry |
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Product Specifications for Mag-Fura-2 AM
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Chemical Name
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Background References
References are publications that support the biological activity of the product.
- Watanabe Chronic magnesium deficiency causes reversible mitochondrial permeability transition pore opening and impairs hypoxia tolerance in the rat heart. J.Pharmacol.Sci. 2022 PMID: 35063139
- Cheng Variability of mitochondrial energy balance across brain regions. J.Neurochem. 2021 PMID: 33190229
- Schütz Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos. Cell Rep. 2021 PMID: 34686339
Product Documents for Mag-Fura-2 AM
Certificate of Analysis
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Product Specific Notices for Mag-Fura-2 AM
For research use only
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