MagCellect Mouse CD3+ T Cell Isolation Kit
MagCellect Mouse CD3+ T Cell Isolation Kit Summary
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Background: CD3
The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.
Citations for MagCellect Mouse CD3+ T Cell Isolation Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 7
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Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway
Authors: Khalid Z Matalka
Molecules, 2016;21(6):. 2016
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Intrinsic Photosensitivity Enhances Motility of T Lymphocytes
Sci Rep, 2016;6(0):39479. 2016
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Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12-interferon-gamma pathway.
Authors: Badr M, Qinna N, Qadan F, Matalka K
Onco Targets Ther, 2014;7(0):193-201. 2014
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T-cell reconstitution during murine acquired immunodeficiency syndrome (MAIDS) produces neuroinflammation and mortality in animals harboring opportunistic viral brain infection.
Authors: Mutnal, Manohar, Schachtele, Scott J, Hu, Shuxian, Lokensgard, James R
J Neuroinflammation, 2013;10(1):98. 2013
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hsBAFF regulates proliferation and response in cultured CD4(+) T lymphocytes by upregulation of intracellular free Ca(2+) homeostasis.
Authors: Wen L, Chen SJ, Zhang W, Ma HW, Zhang SQ, Chen L
Cytokine, 2011;53(2):215-22. 2011
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Cytokine-dependent regulation of NADPH oxidase activity and the consequences for activated T cell homeostasis.
Authors: Purushothaman D, Sarin A
J. Exp. Med., 2009;206(7):1515-23. 2009
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Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells.
Authors: Bheeshmachar G, Purushotaman D, Sade H, Gunasekharan V, Rangarajan A, Sarin A
J. Immunol., 2006;177(8):5041-50. 2006
FAQs
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When using MacCellect Cell Isolation kits (MAGM*** or MAGH***), why is it important to lyse red blood cells before starting the cell isolation protocol?
It is important to remove red blood cells before the isolation protocol using MagCellect isolation kits because not doing so can cause a poorer yield of selected cells. Red blood cells become sticky during the incubation protocols and may interfere with the interactions needed for removal of unwanted populations.
Supplemental Cell Selection Products
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