Margatoxin

Catalog # Availability Size / Price Qty
3563/100U
Margatoxin
1 Image
Description: Potent KV1.3 channel blocker
Alternative Names: MgTX

Purity: ≥95%

Product Details
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Biological Activity

Margatoxin is a potent KV1.3 channel blocker (IC50 = 36 pM). Displays no effect at calcium-activated channels. Reduces VEGF-induced transmembrane calcium influxes and nitric oxide production in human endothelial cells.

Technical Data

M.Wt:
4178.96
Formula:
C178H286N52O50S7
Sequence:
TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH

(Modifications: Disulfide bridges: 7-29, 13-34, 17-36)

Solubility:
Soluble to 0.50 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
145808-47-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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