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Margatoxin

   
Product Datasheet
Catalog Number:3563
Alternate Names:MgTX
Chemical Name:
Product Details
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Biological Activity
Potent KV1.3 channel blocker (IC50 = 36 pM). Displays no effect at calcium-activated channels. Reduces VEGF-induced transmembrane calcium influxes and nitric oxide production in human endothelial cells.
Technical Data
  • M.Wt:
    4178.96
  • Formula:
    C178H286N52O50S7
  • Sequence:
    TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH

    (Modifications: Disulfide bridge between 7 - 29, 13 - 34, 17 - 36)

  • Solubility:
    Soluble to 0.50 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    145808-47-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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