Mastoparan (CAS 72093-21-1): R&D Systems
Catalog Number: 1192
Biological Activity
Peptide activator of Gi and Go.
Technical Data
  • M.Wt:
    1479
  • Formula:
    C70H131N19O15
  • Sequence:
    INLKALAALAKKIL

    (Modifications: Leu-14 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    72093-21-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go.
    Higashijima and Ros
    J.Biol.Chem., 1991;266:12655
  2. Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin.
    Raynor et al.
    J.Biol.Chem., 1991;266:2753
  3. The mechanism of inhibition of the Ca2+-ATPase by mastoparan.
    Longland et al.
    J.Biol.Chem., 1999;274:14799
  4. G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides.
    Mousli et al.
    TiPS, 1990;11:358

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