Biological Activity
Mastoparan is a peptide activator of Gi and Go.Technical Data
(Modifications: Leu-14 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Background References
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Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go.
Higashijima and Ros
J.Biol.Chem., 1991;266:12655 -
The mechanism of inhibition of the Ca2+-ATPase by mastoparan.
Longland et al.
J.Biol.Chem., 1999;274:14799 -
G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides.
Mousli et al.
TiPS, 1990;11:358 -
Membrane interactions of amphiphilic polypeptides mastoparan, melittin, plymixin B and cardiotoxin.
Raynor et al.
J.Biol.Chem., 1991;266:2753
Product Datasheets
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Citation for Mastoparan
The citations listed below are publications that use Tocris products. Selected citations for Mastoparan include:
1 Citation: Showing 1 - 1
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A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression.
Authors: Akoume Et al.
Sci Rep 2019;9:10074
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