MCL 0020
Tocris Bioscience | Catalog # 3438
Selective MC4 receptor antagonist
Discontinued Product
3438 has been discontinued.
View all Melanocortin Receptor Antagonists products.
Key Product Details
Description
Selective MC4 receptor antagonist
Product Description
MCL 0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no effect on food intake in free-feeding rats. Exhibits anxiolytic-like activity in vivo.
Product Specifications for MCL 0020
Molecular Weight
609.73
Formula
C34H39N7O4
Storage
Store at -20°C
CAS Number
475498-26-1
PubChem ID
9938789
InChI Key
FJFLYSMWSRRMRO-FRXPANAUSA-N
SMILES
CC(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](CC1=CC2=CC=CC=C2C=C1)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 2mg/ml in 25% ethanol / water |
Calculators
Background References
References are publications that support the biological activity of the product.
- Chaki Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents. Eur.J.Pharmacol. 2003 PMID: 12909200
Product Documents for MCL 0020
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for MCL 0020
For research use only
Related Research Areas
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