MDL 12330A hydrochloride
Tocris Bioscience | Catalog # 1436
Key Product Details
Description
Product Description
MDL 12330A hydrochloride is an inhibitor of adenylyl cyclase. Also inhibits cAMP and cGMP phosphodiesterases, and blocks slow extracellular and store-operated Ca2+ entry into cells.
Product Specifications for MDL 12330A hydrochloride
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 7.54 | 20 | |
| Ethanol | 7.54 | 20 |
Preparing Stock Solutions for MDL 12330A hydrochloride
The following data is based on the product molecular weight 377.01.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.2 mM | 13.26 mL | 66.31 mL | 132.62 mL |
| 1 mM | 2.65 mL | 13.26 mL | 26.52 mL |
| 2 mM | 1.33 mL | 6.63 mL | 13.26 mL |
| 10 mM | 0.27 mL | 1.33 mL | 2.65 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.
- Hunt and Evans RMI 12330A, an inhibitor of cyclic nucleotide phosphodiesterases and adenylate cyclase in kidney preparations. Biochim.Biophys.Acta 1980 PMID: 6256001
- van Rossum Ca2+ entry mediated by store depletion, S-nitrosylation, and TRP3 channels. Comparison of coupling and function. J.Biol.Chem. 2000 PMID: 10878007
- Guellaen RMI 12330 A, an inhibitor of adenylate cyclase in rat liver. Biochim.Biophys.Acta 1977 PMID: 911855
Product Documents for MDL 12330A hydrochloride
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for MDL 12330A hydrochloride
For research use only
Citations for MDL 12330A hydrochloride
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