MDL 28170

  ( 2 citations )    
Product Datasheet
Catalog Number:1146
Chemical Name:N-[N-[(Phenylmethoxy)carbonyl]-L-valyl]-phenylalaninal
Product Details
Citations (2)
Reviews
Biological Activity
Potent, selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively) that does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo.
Technical Data
  • M.Wt:
    382.45
  • Formula:
    C22H26N2O4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >95
  • Storage:
    Store at -20°C
  • CAS No:
    88191-84-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for MDL 28170 include:

2 Citations: Showing 1 - 2
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  1. ANO1 interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer.
    Authors: Bill Et al.
    J Neurosci  2015;6:9173
  2. Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis.
    Authors: Schubert Et al.
    Acta Neuropathol  2014;128:835

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