Meclizine dihydrochloride

Product Datasheet
Catalog Number:4245
Alternate Names:Meclozine
Chemical Name:1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazine dihydrochloride
Product Details
Supplemental Products
Biological Activity
Human pregnane X receptor (hPXR) agonist; stronger activator of hPXR than rat PXR. Increases hPXR target gene expression in human hepatocyte primary cultures. Also acts as a histamine H1 receptor antagonist. Confers neuroprotection in models of polyQ toxicity.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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