Chemical Name: 17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione
Biological ActivityMegestrol Acetate is a synthetic progesterone analog. Dose-dependently inhibits growth of HepG2 cells (IC50 = 260 μM) in vitro and in vivo and reduces tumor volume. High dosages improve weight gain in tumor-bearing nude mice. Orally bioavailable.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Megestrol acetate in cancer anorexia and weight loss.
Tchekmedyian et al.
The effect of mege. acetate on growth of HepG2 cells in vitro and in vivo.
Zhang and Chow
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