Catalog Number: 3550
Chemical Name: N-Acetyl-5-methoxytryptamine
Biological Activity
Endogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair.
    Fischer et al.
    Exp.Dermatol., 2008;17:713
  2. Melatonin and melatonergic drugs on sleep: possible mechanisms of action.
    Cardinali et al.
    Int.J.Neurosci., 2009;119:821
  3. Thirty four years since the discovery of gastrointestinal melatonin.
    J.Physiol.Pharmacol., 2008;59:33

The citations listed below are publications that use Tocris products. Selected citations for Melatonin include:

Showing Results 1 - 2 of 2

  1. Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.
    Authors: Chen Et al.
    Toxicol Sci
  2. Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons.
    Authors: Huang Et al.
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information