Catalog Number: 3550
Chemical Name: N-Acetyl-5-methoxytryptamine
Biological Activity
Endogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair.
    Fischer et al.
    Exp.Dermatol., 2008;17:713
  2. Melatonin and melatonergic drugs on sleep: possible mechanisms of action.
    Cardinali et al.
    Int.J.Neurosci., 2009;119:821
  3. Thirty four years since the discovery of gastrointestinal melatonin.
    J.Physiol.Pharmacol., 2008;59:33

The citations listed below are publications that use Tocris products. Selected citations for Melatonin include:

2 Citations: Showing 1 - 2
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  1. Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.
    Authors: Chen Et al.
    Toxicol Sci 2014;20:1298
  2. Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons.
    Authors: Huang Et al.
    Nature 2010;114:124

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