Chemical Name: N-Acetyl-5-methoxytryptamine
Biological ActivityMelatonin is an endogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Thirty four years since the discovery of gastrointestinal melatonin.
Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair.
Fischer et al.
Melatonin and melatonergic drugs on sleep: possible mechanisms of action.
Cardinali et al.
Citations for Melatonin
The citations listed below are publications that use Tocris products. Selected citations for Melatonin include:
7 Citations: Showing 1 - 7
Melatonin and Leishmania amazonensis Infection Altered miR-294, miR-30e, and miR-302d Impacting on Tnf, Mcp-1, and Nos2 Expression.
Authors: Fernandes Et al.
Front Cell Infect Microbiol 2019;9:60
A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression.
Authors: Akoume Et al.
Sci Rep 2019;9:10074
Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS Rats.
Authors: Hou Et al.
Front Cell Neurosci 2017;11:98
The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice.
Authors: Costa Et al.
Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.
Authors: Chen Et al.
Toxicol Sci 2014;20:1298
Comparative cytotoxicity and intracellular accumulation of five polybrominated diphenyl ether congeners in mouse cerebellar granule neurons.
Authors: Huang Et al.
Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels.
Authors: Giordano Et al.
Toxicol Appl Pharmacol 2008;232:161
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