Methoxy-X04

Catalog # Availability Size / Price Qty
4920/10
4920/50

15% Off Limited-time Savings on Your Reagents, Assays, and Kits
Now through September 27th, you can save 15% on Bio-Techne reagents, assays, and kits (including Novus, Tocris, and R&D Systems). Use promotion code SAVE15 at checkout on orders over $1,000. See terms and conditions for offer details.

Methoxy-X04 | CAS No. 863918-78-9 | Fluorescent Amyloid B Probes
1 Image
Description: Fluorescent amyloid β detector; brain penetrant

Chemical Name: 4,4'-[(2-methoxy-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol

Purity: ≥98%

Product Details
Citations (8)
Reviews (1)

Biological Activity

Methoxy-X04 is a fluorescent amyloid β (Aβ) probe for the detection and quantification of plaques, tangles and cerebrovascular amyloid. Methoxy-X04 displays high in vitro binding affinity (Ki = 26.8 nM); binds selectively to fibrillar β-sheet deposits. Methoxy-X04 is a derivative of Congo Red (Cat. No. 5167). Methoxy-X04 can be used for in vivo Aβ plaque labeling. Methoxy-X04 co-localizes with CD68+ phagosomes in plaque-associated Iba1+ microglia; and it labels molecularly distinct plaque-associated microglia populations. Brain penetrant.

Technical Data

M.Wt:
344.4
Formula:
C23H20O3
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
863918-78-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Methoxy-X04

Average Rating: 4 (Based on 1 Review)

5 Star
0%
4 Star
50%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Methoxy-X04?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Methoxy staining for hippocampal slices
By Anonymous on 02/05/2020
Species: Mouse

The hippocampal slices from mice brain was dyed with methoxy X04 in PBS-EtOH solution. The slices were kept in dark and were then mounted with dako vector mounting media


Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.