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Methylene Blue

3213 1 Review Datasheet / COA / SDS
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3213/50
Methylene Blue | CAS No. 61-73-4 | Histology Stains
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Description: Biological stain

Chemical Name: 3,7-bis(Dimethylamino)phenazathionium chloride

Product Details
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Methylene Blue is a biological stain and redox indicator. Inhibits tau filament formation (IC50 = 1.9 μM). Also inhibits soluble guanylyl cyclase.

Technical Data

M.Wt:
319.85
Formula:
C16H18ClN3S
Solubility:
Soluble to 10 mM in water and to 10 mM in DMSO
Storage:
Store at RT
CAS No:
61-73-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Comparison of two soluble guanylyl cyclase inhibitors, methylene boue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea.
    Hwang et al.
    Br.J.Pharmacol., 1998;125:1158
  2. Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins.
    Taniguchi et al.
    J.Biol.Chem., 2005;280:7614
  3. Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines.
    Wischik et al.
    Neurobiology, 1996;93:11213

Product Datasheets

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Reconstitution Calculator

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Methylene blue was used to prepare Eosin Methylene Blue agar plate
By Anonymous on 11/13/2018
Application: Species: Human

Methylene blue was used to prepare Eosin Methylene Blue (EMB) agar plate. Excellent product.

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