Chemical Name: 3,7-bis(Dimethylamino)phenazathionium chloride
Biological ActivityMethylene Blue is a biological stain and redox indicator. Inhibits tau filament formation (IC50 = 1.9 μM). Also inhibits soluble guanylyl cyclase.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Comparison of two soluble guanylyl cyclase inhibitors, methylene boue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea.
Hwang et al.
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins.
Taniguchi et al.
Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines.
Wischik et al.
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Methylene blue was used to prepare Eosin Methylene Blue (EMB) agar plate. Excellent product.