Methylene Blue

Catalog #: 3213 Datasheet / COA / SDS

Discontinued Product

3213 has been discontinued.
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Methylene Blue | CAS No. 61-73-4 | Histology Stains
1 Image
Description: Biological stain; also neuroprotective and antimalarial

Chemical Name: 3,7-bis(Dimethylamino)phenazathionium chloride

Product Details

Biological Activity

Methylene Blue is a biological stain and redox indicator. Methylene blue inhibits monoamine oxidase A, tau filament formation and nitric oxide synthase (IC50 values = 0.07 μM, 1.9 μM and 5.3 μM, respectively), and inhibits guanylate cyclase. Methylene Blue delays senescence and stimulates proliferation of fibroblasts and skin cells. In vitro, Methylene Blue promotes wound healing, upregulates elastin expression and production, increases synthesis of heme, is neuroprotective (EC50 = 0.18 nM) and rescues the loss of dopaminergic neurons induced by Rotenone (Cat. No. 3616). Also antimalarial.

Technical Data

Soluble to 10 mM in water and to 10 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
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Reconstitution Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).


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