Methylprednisolone

Catalog # Availability Size / Price Qty
4819/50
Cat.No. 4819 - Methylprednisolone | C22H30O5 | CAS No. 83-43-2
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Description: Glucocorticoid receptor agonist

Chemical Name: 11β,17β,21-Trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione

Purity: ≥99%

Product Details
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Biological Activity

Glucocorticoid receptor (GR) agonist. Displays anti-inflammatory and antioxidant properties. Attenuates apoptosis in oligodendrocytes after injury stimuli. Upregulates expression of Bcl-xL via direct binding of the GR/STAT5 complex. Neuroprotective.

Technical Data

M.Wt:
374.47
Formula:
C22H30O5
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
83-43-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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