Catalog Number: 1356
Chemical Name: N,N,N-Triethyl-2-[4-(2-phenylethenyl)phenoxy]ethanaminium iodide
Biological Activity
A selective antagonist for neuronal α7 subunit- containing nAChR subtypes. Inhibits α-Bgtx binding to chick α7 and α4β2 subtypes with Ki values of 106 nM and 84 μM respectively.
Technical Data
  • M.Wt:
    451.39
  • Formula:
    C22H30NOI
  • Solubility:
    Soluble to 20 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    77257-42-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. 4-Oxystilbene compounds are selective ligands for neuronal nicotinic abungarotoxin receptors.
    Gotti et al.
    Br.J.Pharmacol., 1998;124:1197
  2. Selective effects of a 4-oxystilbene derivative on wild and mutant neuronal chick α7 nicotinic receptor.
    Maggi et al.
    Br.J.Pharmacol., 1999;126:285
Citations:

The citations listed below are publications that use Tocris products. Selected citations for MG 624 include:

1 Citations: Showing 1 - 1

  1. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A.
    Authors: Cassilly Et al.
    Int J Clin Exp Pathol 2016;11:e0154932

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