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MG 624

Catalog #: 1356
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1356/10
1356/50
MG 624 | CAS No. 77257-42-2 | Nicotinic (a7) Receptor Antagonists
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Description: α7 neuronal nAChR antagonist

Chemical Name: N,N,N-Triethyl-2-[4-(2-phenylethenyl)phenoxy]ethanaminium iodide

Purity: ≥98%

Product Details
Citations (3)
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Biological Activity

MG 624 is a selective antagonist for neuronal α7 subunit- containing nAChR subtypes. Inhibits α-Bgtx binding to chick α7 and α4β2 subtypes with Ki values of 106 nM and 84 μM respectively.

Technical Data

M.Wt:
451.39
Formula:
C22H30NOI
Solubility:
Soluble to 20 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
77257-42-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Complete Your Experiment

Human nAChR alpha 7/CHRNA7 (NP_000737) VersaClone cDNA
Cat # RDC0282

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Citations for MG 624

The citations listed below are publications that use Tocris products. Selected citations for MG 624 include:

3 Citations: Showing 1 - 3

  1. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.
    Authors: Dolma Et al.
    Cancer Cell  2016;29:859
  2. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A.
    Authors: Cassilly Et al.
    Int J Clin Exp Pathol  2016;11:e0154932
  3. Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin.
    Authors: Chang Et al.
    Sci Rep  2015;5:10256

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VersaClone cDNA Plasmids

Human nAChR alpha 7/CHRNA7 (NP_000737) VersaClone cDNA

RDC0282

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