channel blocker with moderate selectivity for T-type Ca2+
channels displaying IC50
values of 2.7 μ
M and 18.6 μ
M for T-type and L-type channels respectively. Antihypertensive agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
In vitro pharmacologic profile of Ro 40-5967, a novel Ca2+ channel blocker with potent vasodilator but weak inotropic action.
Osterrieder and Holck
Hemodynamic profile of Ro 40-5967 in conscious rats: comparison with diltiazem, verapamil, and amlodipine.
Veniant et al.
The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels.
Mehrke et al.
The citations listed below are publications that use Tocris products. Selected citations for Mibefradil dihydrochloride include:
Showing Results 1 - 6 of 6