Mibefradil dihydrochloride

Catalog # Availability Size / Price Qty
2198/10
2198/50
Mibefradil dihydrochloride | CAS No. 116666-63-8 | Cav3.x Channel Blockers
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Description: CaV3.x blocker
Alternative Names: Ro 40-5967

Chemical Name: (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetoacetate dihydrochloride

Purity: ≥97%

Product Details
Citations (9)
Reviews (1)

Biological Activity

Ca2+ channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50 values of 2.7 μM and 18.6 μM for T-type and L-type channels respectively. Antihypertensive agent.

Technical Data

M.Wt:
568.56
Formula:
C29H38FN3O3.2HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C
CAS No:
116666-63-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Mibefradil dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Mibefradil dihydrochloride include:

9 Citations: Showing 1 - 9

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Mibefradil dihydrochloride used on T type calcium channels
By Anonymous on 02/13/2019
Application: Species: Human

Mibefradil dihydrochloride used on T type calcium channels that aid in mediating calcium influx into cells after an action potential or depolarizing signal. The entry of calcium into various cells has many different physiological responses associated with it.


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