Potent cAMP phosphodiesterase inhibitor (IC50
= 56 nM for inhibition of PDE III). Has inotropic and vasodilator effects following oral or intravenous administration in vivo
. Also available as part of the Phosphodiesterase Inhibitor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Characterization of the cardiotonic effects of milrinone, a new and potent cardiac bipyridine, on isolated tissues from several animal species.
Alousi et al.
The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in bovine tracheal smooth muscle and the functional effects of selective inhibitors.
Shahid et al.
Photoaffinity labelling of cyclic GMP-inhibited phosphodiesterase (PDE III) in human and rat platelets and rat tissues: effects of phosphodiesterase inhibitors.
Tang et al.
The citations listed below are publications that use Tocris products. Selected citations for Milrinone include:
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