Müllerian inhibiting substance (MIS), also named anti-Müllerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.
MIS/AMH Antibody (016) - Azide and BSA Free
Novus Biologicals | Catalog # NBP2-90332
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Human
Applications
ELISA, Sandwich ELISA Capture
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 016 expressed in HEK293
Format
Azide and BSA Free
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Product Specifications
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human MIS/AMH (Accession#: NP_000470.2; Leu25-Arg560).
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Description
This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Applications for MIS/AMH Antibody (016) - Azide and BSA Free
Application
Recommended Usage
ELISA
1:5000-1:10000
Sandwich ELISA Capture
1:250-1:2000
Application Notes
In a sandwich ELISA, MIS/AMH Antibody (016) can be used as capture antibody when paired with NBP2-90330.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
0.2 um filtered solution in PBS
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: MIS/AMH
Long Name
Mullerian-inhibiting Substance/Anti-Mullerian Hormone
Alternate Names
AMH
Gene Symbol
AMH
Additional MIS/AMH Products
Product Documents for MIS/AMH Antibody (016) - Azide and BSA Free
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for MIS/AMH Antibody (016) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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Protocols
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