Mitochondrial fusion promoter M1
Chemical Name: 4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol
Biological ActivityMitochondrial fusion promoter M1 is a mitochondrial fusion promoter. Protects cells from mitochondrial fragmentation-associated cell death. Induces mitochondrial fusion in effector T cells imposing a memory T cell morphology. Improves cellular respiration and potentiates glucose-stimulated insulin-secretion in cholesterol-exposed pancreatic β cells. Mitochondrial fusion promoter M1 also enhances mitochondrial dynamics and transport velocity in axons of the sciatic nerve in vitro and enhances axon regeneration in the optic nerve in an in vivo model of nerve damage.
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Restoring mitochondrial function: a small molecule-mediated approach to enhance glucose stimulated insulin secretion in cholesterol accumulated pancreatic beta cells.
Asalla et al.
A small molecule promotes mitochondrial fusion in mammalian cells.
Wang et al.
Mitochondrial dynamics controls T cell fate through metabolic programming.
Buck et al.
Citation for Mitochondrial fusion promoter M1
The citations listed below are publications that use Tocris products. Selected citations for Mitochondrial fusion promoter M1 include:
1 Citation: Showing 1 - 1
Aspartate Alleviates Colonic Epithelial Damage by Regulating Intestinal Stem Cell Proliferation and Differentiation via Mitochondrial Dynamics.
Authors: Dan Et al.
Mol Nutr Food Res 2022;66:e2200168
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