ML 133 hydrochloride

Catalog # Availability Size / Price Qty
4549/10
4549/50
ML 133 hydrochloride | CAS No. 1222781-70-5 | Inward Rectifier Potassium Channel Blockers
1 Image
Description: Kir2 channel blocker

Chemical Name: N-[(4-Methoxyphenyl)methyl]-1-naphthalenemethanamine hydrochloride

Purity: ≥99%

Product Details
Citations (3)
Reviews (1)

Biological Activity

Selective blocker of inwardly rectifying Kir2 potassium channels (IC50 values are 1.8, 2.8, 2.9 and 4.0 μM at pH 7.4 for mKir2.1, hKir2.6, hKir2.2 and hKir2.3 respectively). Exhibits no effect on rKir1.1 (IC50 > 300 μM); displays weak activity at hKir7.1 and rKir4.1 (IC50 values are 33 and 76 μM).

Technical Data

M.Wt:
313.82
Formula:
C19H19NO.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1222781-70-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for ML 133 hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for ML 133 hydrochloride include:

3 Citations: Showing 1 - 3

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for ML 133 hydrochloride

Average Rating: 5 (Based on 1 Review)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used ML 133 hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


ML 133 hydrochloride was used on Calcium-activated 6T & 1P potassium channels
By Anonymous on 02/27/2019
Application: Species: Human

ML 133 hydrochloride was used on Calcium-activated 6T & 1P potassium channels. The product works ideally on cell culture labs and would highly recommend.


Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.