Nrf2 activator; inhibits Nrf2/Keap1 interaction (Kd
= 1 μ
M). Promotes Nrf2 nuclear translocation and induces antioxidant response element (ARE) activity in vitro
. Cell permeable.
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All Tocris products are intended for laboratory research use only.
Oxidative stress in Alzheimer's disease: are we connecting the dots?
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Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction.
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