ML 335

Catalog # Availability Size / Price Qty
6887/10
6887/50
Two-P Potassium Channels Activators Small Molecule
1 Image
Description: Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator

Chemical Name: N-[(2,4-Dichlorophenyl)methyl]-4-[(methylsulfonyl)amino]benzamide

Purity: ≥98%

Product Details
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Biological Activity

Selective K2P2.1 (TREK-1; KCNK2) and K2P10.1 (TREK-2; KCNK10) activator (EC50 values of 14.3 μM and 5.2 μM, respectively); directly stimulates the C-type gate via the K2P modulator pocket. Does not activate K2P4.1 (TRAAK).

Technical Data

M.Wt:
373.25
Formula:
C15H14Cl2N2O3S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
825658-06-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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