ML 365

Catalog # Availability Size / Price Qty
5337/50
5337/10
ML 365 | CAS No. 947914-18-3 | Two-P Potassium Channels Blockers
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Description: Potent and selective K2P3.1 (TASK-1) channel blocker

Chemical Name: 2-Methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide

Purity: ≥99%

Product Details
Citations (3)
Reviews (1)

Biological Activity

Potent and selective TASK-1 (K2P3.1/KCNK3) channel blocker (IC50 values are 4 and 390 nM at TASK-1 and TASK-3, respectively). Displays little or no inhibition at Kir2.1, voltage-gated potassium channels, KCNQ2 and KV11.1 (hERG).

Technical Data

M.Wt:
360.41
Formula:
C22H20N2O3
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
947914-18-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for ML 365

The citations listed below are publications that use Tocris products. Selected citations for ML 365 include:

3 Citations: Showing 1 - 3

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Reviews for ML 365

Average Rating: 5 (Based on 1 Review)

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Ml 365 used to study the channel blocking activity on K2p1.1 channels
By Anonymous on 11/27/2018
Application: Species: Human

This product was used to study the channel blocking activity on K2p1.1 channels. It was identified that it shows certain degree of channel blocking although that is not concentration dependent. Would buy again as the results obtained were reproducible at every trial study.


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