MLS 1547

Catalog # Availability Size / Price Qty
6171/25
6171/5
MLS 1547 | CAS No. 315698-36-3 | Dopamine D2 Receptor Agonists
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Description: G protein-biased D2 partial agonist

Chemical Name: 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol

Purity: ≥98%

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Biological Activity

MLS 1547 is a G protein-biased D2 receptor partial agonist (Ki = 1.2 μM). Stimulates D2 receptor G protein-mediated signaling and acts as an antagonist of dopamine-mediated β-arrestin recruitment at D2 receptors.

Technical Data

M.Wt:
354.83
Formula:
C19H19ClN4O
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
315698-36-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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