Butyrophilin 1A1 (BTN1A1) is a B7-related protein in a family that may show co-stimulatory/inhibitory function. BTN1A1 binds to xanthine oxidoreductase (XOR) and is essential in the control of milk fat globule secretion. The B30.2 domain of butyrophilins can sense changes in intracellular phopho-antigen (pAg) concentrations. Its binding to pAg leads to gamma-delta T cell activation. BTN1A1 inhibits CD4+ T cell proliferation and reduces IL-2 and IFN-gamma expression. BTN1A1 has a protective effect against the development of experimental autoimmune encephalomyelitis (EAE).
Mouse BTN1A1 (NP_038511) VersaClone cDNA
R&D Systems | Catalog # RDC0820
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: BTN1A1/Butyrophilin
Alternate Names
BTN, BTN1A1
Gene Symbol
BTN1A1
UniProt
Additional BTN1A1/Butyrophilin Products
Product Documents for Mouse BTN1A1 (NP_038511) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse BTN1A1 (NP_038511) VersaClone cDNA
For research use only
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