Mouse CD200R1L Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB10198N Datasheet / COA / SDS
Recombinant Monoclonal Antibody
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Product Details
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Mouse CD200R1L Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Detects mouse CD200R1L in direct ELISAs.
Recombinant Monoclonal Rabbit IgG Clone # 2692A
Protein A or G purified from cell culture supernatant
Mouse myeloma cell line NS0-derived mouse CD200R1L
Accession # Q6XJV6.1
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)


Recommended Concentration
Flow Cytometry
0.25-1 µg/106 cells
HEK293 human embryonic kidney cell line transfected with mouse CD200R1L and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution default not known
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD200R1L

CD200 Receptor 2 (CD200R2), or CD200R1L, is a type I transmembrane receptor for the CD200 cell surface glycoprotein. Mature CD200R2 consists of an extracellular domain (ECD) containing an Ig-like V-type domain and an Ig-like C2-type domain, a transmembrane segment and a short cytoplasmic domain. The ECD of mouse CD200R2 shares a 76% and 63% amino acid (aa) identity with the rat and human ECD, respectively. CD200R2 is strongly expressed on resting mast cells but deceased upon activation via Fc epsilon R1. It is also observed on monocytes, bone marrow-derived dendritic cells and TH2 cells (1, 2, 4). It has been demonstrated CD200R2 can interact with CD200 (3) and signal through adaptor protein, DAP12, via its lysine residue in the transmembrane region (2). In addition, it has been reported CD200 and CD200R2 interaction alters dendritic cell differentiation and enhances induction of CD4+CD25+Foxp3+ regulatory T cells in mouse transplant model (5).

  1. Wright, G. et al. (2003) J. Immunol. 171:3034.
  2. Voehringer, D. (2004) J. Biol. Chem. 279(52):54117.
  3. Gorczynski, R. et al. (2004) J. Immunol. 172:7744.
  4. Minas, K. (2006) Crit Rev Immunol 26(3):213.
  5. Gorczynski, R. et al. (2008) J. Immunol. 180(9):5946.
Long Name
CD200 Receptor 1 Like
Entrez Gene IDs
344807 (Human); 271375 (Mouse); 501779 (Rat)
Alternate Names
cell surface glycoprotein CD200 receptor 2; CD200 receptor 1-like; CD200R1L; CD200R2; CD200RLa

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Product Specific Notices

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.


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