The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, CysLTR1 and CysLTR2. Both receptors are members of the superfamily of G protein-coupled receptors. Activation of CysLTR1 by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Mouse CysTLR1 (NP_067451) VersaClone cDNA
R&D Systems | Catalog # RDC0391
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Cysteinyl Leukotriene R1/CysLTR1
Long Name
Cysteinyl Leukotriene Receptor 1
Alternate Names
CysLT1, CysLTR1, Cysteinyl LeukotrieneR1, HG55, HMTMF81, LTD4 Receptor
Gene Symbol
CYSLTR1
UniProt
Additional Cysteinyl Leukotriene R1/CysLTR1 Products
Product Documents for Mouse CysTLR1 (NP_067451) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse CysTLR1 (NP_067451) VersaClone cDNA
For research use only
Related Research Areas
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