Mouse Epimorphin/Syntaxin 2 Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAF2568
Product Details
Citations (1)
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Mouse Epimorphin/Syntaxin 2 Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Epimorphin/Syntaxin 2 in Western blots. In Western blots, approximately 40% cross‑reactivity with recombinant human Epimorphin is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse Epimorphin/Syntaxin 2
Met1-Arg189
Accession # Q00262
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse Epimorphin/Syntaxin 2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Reconstitution Calculator

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Epimorphin/Syntaxin 2

Epimorphin, also known as syntaxin 2, is a member of the highly conserved syntaxin family. It is a type IV integral membrane protein with a C-terminal membrane anchor, and an N-terminal functional domain. Epimorphin can assume membrane topology with the functional domain localized extracellularly or to the cytoplasmic face. Extracellular Epimorphin functions in morphogenesis while intracellular syntaxin 2 functions as a vesicle fusion protein. Mouse Epimorphin functional domain shares 97% and 91% amino acid sequence homology with rat and human Epimorphin, respectively.

Entrez Gene IDs
2054 (Human); 13852 (Mouse)
Alternate Names
EPIMepimorphin; Epimorphin; EPM; STX2; STX2AMGC51014; STX2Bsyntaxin-2; STX2CEpimorphin; Syntaxin 2

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Citation for Mouse Epimorphin/Syntaxin 2 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Overexpression of extracellular epimorphin leads to impaired epidermal differentiation in HaCaT keratinocytes.
    Authors: Okugawa Y, Hirai Y
    J. Invest. Dermatol., 2008-02-14;128(8):1884-93.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Western Blot

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