Mouse Klre-1 PE-conjugated Antibody

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Detection of Klre‑1 in NKp46+Mouse Splenocytes by Flow Cytometry.
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Mouse Klre-1 PE-conjugated Antibody Summary

Species Reactivity
Detects mouse Klre-1 in ELISAs.
Monoclonal Rat IgG2B Clone # 854929
Protein A or G purified from hybridoma culture supernatant
Chinese hamster ovary cell line CHO derived recombinant mouse Klre-1
Accession # NP_705818
Supplied in a saline solution containing BSA and Sodium Azide.
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)


Recommended Concentration
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of Klre-1 antibody in NKp46<SUP>+</SUP>Mouse Splenocytes antibody by Flow Cytometry. View Larger

Detection of Klre‑1 in NKp46+Mouse Splenocytes by Flow Cytometry. NKp46+mouse splenocytes were stained with Rat Anti-Mouse Klre-1 PE-conjugated Mono-clonal Antibody (Catalog # FAB7099P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: Klre-1

Killer cell lectin-like receptor family E member 1 (Klre-1), also called NKG2I (NKG2 family member I), is a 24-28 kDa member of the NKG2/KLR family of proteins. It is expressed on mouse NK and NKT cells, and appears to serve as one component of two novel heterodimeric cell surface receptors. When complexed to KLRI1, Klre-1 inhibits NK cell cytotoxic activity. When complexed to KLRI2, Klre-1 activates NK cells, inducing IFN-gamma production and the activation of a cytolytic program. Although Klre-1 preferentially associates noncovalently with NLRI1 and I2, it apparently will form disulfide-linked homodimers in the absence of its heterodimer partners. Mouse Klre-1 is a 226 amino acid (aa) type II transmembrane protein. It contains an N-terminal cytoplasmic segment (aa 1-68) plus a 133 aa extracellular region (aa 94-226) that possesses one C-type lectin domain (aa 110-226). Over aa 94-226, mouse Klre-1 shares 82% aa identity with rat Klre-1. There does not appear to be a human structural ortholog to mouse Klre-1.

Long Name
Killer Cell Lectin-like Receptor Family E Member 1
Entrez Gene IDs
243655 (Mouse)
Alternate Names
CD94; Klre1; Klre-1; NKG2I

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