Mps BAY 2a

Tocris Bioscience | Catalog # 5562

Potent and selective Mps1 kinase inhibitor
Tocris Bioscience
Discontinued Product
5562 has been discontinued. View all TTK/Mps1 Kinase Inhibitors products.

Key Product Details

Description

Potent and selective Mps1 kinase inhibitor
View all TTK/Mps1 Kinase Inhibitors »

Product Description

Potent and selective Mps1 inhibitor (IC50 = 1 nM for human enzyme). Selective for Mps1 over a panel of 220 kinases. Differentially inhibits human colon carcinoma cell proliferation. Blocks cell cycle progression by preventing spindle assembly checkpoint activation. Induces apoptosis.

Product Specifications for Mps BAY 2a

Molecular Weight

476.57

Formula

C29H28N6O

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-Cyclopropyl-4-[8-[(2-methylpropyl)amino]-6-(5-quinolinyl)imidazo[1,2-a]pyrazin-3-yl]benzamide

CAS Number

1382477-96-4

PubChem ID

57381882

InChI Key

MDYKTGNHXNTATG-UHFFFAOYSA-N

SMILES

CC(C)CNC1=NC(C2=CC=CC3=C2C=CC=N3)=CN4C1=NC=C4C5=CC=C(C(NC6CC6)=O)C=C5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 47.66 100
Ethanol 47.66 100

Preparing Stock Solutions for Mps BAY 2a

The following data is based on the product molecular weight 476.57.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.10 mL 10.49 mL 20.98 mL
5 mM 0.42 mL 2.10 mL 4.20 mL
10 mM 0.21 mL 1.05 mL 2.10 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Mps BAY 2a

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Mps BAY 2a

For research use only

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