MRP1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-29106

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all MRP1 Primary Antibodies »

Product Specifications

Immunogen

Between 275 and 325

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MRP1 Antibody - BSA Free

MRP1 Antibody

Immunoprecipitation:MRP1 AntibodyNBP3-29106] -

Immunoprecipitation:MRP1 AntibodyNBP3-29106] -Detection of human MRP1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) prepared using RIPA buffer from Jurkat cells. Antibodies: Affinity purified rabbit anti-MRP1 antibody NBP3-29106 (lot NBP3-29106-1) used for IP at 6 µg per reaction. MRP1 was also immunoprecipitated by rabbit anti-MRP1 antibody BL15927. For blotting immunoprecipitated MRP1, NBP3-29106 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Applications for MRP1 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MRP1

Multidrug Resistance Protein 1 (MRP1) is an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein. MRP1 is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.

Specifically, MRP1 mediates the export of organic anions and drugs from the cytoplasm. It is through this function, that MRP1 is able to confer resistance to anticancer drugs. MRP1 antibodies are therefore useful tools for cancer testing and research.

Long Name

Multi-drug Resistance Protein 1

Alternate Names

ABCC1, GS-X

Gene Symbol

ABCC1

Additional MRP1 Products

Product Documents for MRP1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for MRP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

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Protocols

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FAQs

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