Catalog Number: 0855
Chemical Name: (RS)-α-Methyl-4-tetrazolylphenylglycine
Biological Activity
Group II/group III metabotropic glutamate receptor antagonist, showing selectivity for group II in electrophysiological studies.
Technical Data
  • M.Wt:
    233.23
  • Formula:
    C10H11N5O2
  • Solubility:
    Soluble to 100 mM in 1eq. NaOH
  • Storage:
    Store at RT
  • CAS No:
    169209-66-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors.
    Bedingfield et al.
    Eur.J.Pharmacol., 1996;309:71
  2. Pharmacological antagonism of the actions of group II and group III mGluR agonists in the lateral perforant path of rat hippocampal slices.
    Bushell et al.
    Br.J.Pharmacol., 1996;117:1457
  3. New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord.
    Jane et al.
    Neuropharmacology, 1995;34:851

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