MTPG

Key Product Details

Product Description

MTPG is a group II/group III metabotropic glutamate receptor antagonist, showing selectivity for group II in electrophysiological studies.

Product Specifications for MTPG

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for MTPG

The following data is based on the product molecular weight 233.23.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.29 mL	21.44 mL	42.88 mL
5 mM	0.86 mL	4.29 mL	8.58 mL
10 mM	0.43 mL	2.14 mL	4.29 mL
50 mM	0.09 mL	0.43 mL	0.86 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Bushell Pharmacological antagonism of the actions of group II and group III mGluR agonists in the lateral perforant path of rat hippocampal slices. Br.J.Pharmacol. 1996 PMID: 8730739
• Jane New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology 1995 PMID: 8532166
• Bedingfield Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors. Eur.J.Pharmacol. 1996 PMID: 8864696

Product Documents for MTPG