MTPG
Chemical Name: (RS)-α-Methyl-4-tetrazolylphenylglycine
Biological Activity
MTPG is a group II/group III metabotropic glutamate receptor antagonist, showing selectivity for group II in electrophysiological studies.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Novel potent selective phenylglycine antagonists of metabotropic glutamate receptors.
Bedingfield et al.
Eur.J.Pharmacol., 1996;309:71 -
Pharmacological antagonism of the actions of group II and group III mGluR agonists in the lateral perforant path of rat hippocampal slices.
Bushell et al.
Br.J.Pharmacol., 1996;117:1457 -
New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord.
Jane et al.
Neuropharmacology, 1995;34:851
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