Catalog Number: 5679
Chemical Name: 3'-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine
Biological Activity
Downregulates SnoN and Ski protein expression; promotes TGF-β signaling, independently of MAPK activation. Does not bind ribosomes or block protein synthesis.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in 1eq. HCl
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Downregulation of SnoN oncoprotein induced by antibiotics anisomycin and puromycin positively regulates transforming growth factor-β signals.
    Hernández-Damián et al.
    Biochim.Biophys.Acta., 2013;1830:5049
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