N-Acetylpuromycin

Tocris Bioscience | Catalog # 5679

Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
Tocris Bioscience

Key Product Details

Description

Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
View all Additional TGF-beta Receptor Products »

Product Description

N-Acetylpuromycin downregulates SnoN and Ski protein expression; promotes TGF-β signaling, independently of MAPK activation. Does not bind ribosomes or block protein synthesis.

Product Specifications for N-Acetylpuromycin

Molecular Weight

513.55

Formula

C24H31N7O6

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

3'-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine

CAS Number

22852-13-7

PubChem ID

46173769

InChI Key

LADKVYSQIGJMFP-IYRMOJGWSA-N

SMILES

O[C@@H]1[C@H](NC([C@@H](NC(C)=O)CC4=CC=C(OC)C=C4)=O)[C@@H](CO)O[C@H]1N3C2=NC=NC(N(C)C)=C2N=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 51.35 100
DMSO 51.35 100

Preparing Stock Solutions for N-Acetylpuromycin

The following data is based on the product molecular weight 513.55.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.95 mL 9.74 mL 19.47 mL
5 mM 0.39 mL 1.95 mL 3.89 mL
10 mM 0.19 mL 0.97 mL 1.95 mL
50 mM 0.04 mL 0.19 mL 0.39 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for N-Acetylpuromycin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for N-Acetylpuromycin

For research use only

Related Research Areas

Preeclampsia

Citations for N-Acetylpuromycin

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