N-Formyl-Met-Leu-Phe

Name: N -Formyl-Met-Leu-Phe
Brand: Tocris Bioscience
SKU: 1921
Price: 114 USD
Availability: InStock

Tocris Bioscience | Catalog # 1921

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Citations (11)

Product Documents

Endogenous FPR1 agonist

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Endogenous FPR1 agonist

Alternative Names

fMLP

View all Formyl Peptide Receptor Agonists »

Product Description

N-Formyl-Met-Leu-Phe is an endogenous chemotactic peptide and agonist for the formyl peptide receptor 1 (FPR1) (K_i = 38 nM). Stimulates aggregation of leukocytes.

Product Specifications for N-Formyl-Met-Leu-Phe

Molecular Weight

437.55

Formula

C₂₁H₃₁N₃O₅S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

59880-97-6

PubChem ID

443295

InChI Key

PRQROPMIIGLWRP-BZSNNMDCSA-N

SMILES

CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 4mg/ml in DMSO

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

Mills Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu. J.Biol.Chem. 2000 PMID: 10960471
Spilberg Receptor blockade as a mechanism of deactivation of human neutrophils by pepstatin and formyl-Met-Leu-Phe. Inflammation 1984 PMID: 6325345
Kreutzer Quantitative comparisons of various biological responses of neutrophils to different active and inactive chemotactic factors. Immunopharmacology 1978 PMID: 45788

Product Documents for N-Formyl-Met-Leu-Phe

Certificate of Analysis

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Product Specific Notices for N-Formyl-Met-Leu-Phe

For research use only

Citations for N-Formyl-Met-Leu-Phe

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