Chemical Name: 2-[(3,3-Diphenylpropyl)amino]acetamide hydrochloride
Biological ActivitySelective, non-competitive NMDA receptor antagonist (IC50 = 5 μM); binds to the receptor-associated ion channel and prevents glutamate-induced Ca2+ influx. Displays neuroprotective activity in vivo. Brain-penetrant.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
A novel N-MthD.-aspartate receptor open channel blocker with in vivo neuroprotectant activity.
Planells-Cases et al.
Citation for N20C hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for N20C hydrochloride include:
1 Citation: Showing 1 - 1
Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase.
Authors: Roy Et al.
J Biol Chem 2014;9:e101883
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