Naltriben mesylate

Key Product Details

Product Description

Naltriben mesylate is a selective and potent δ-opioid receptor antagonist (K_i values are 0.013, 19 and 152 nM for δ, μ and κ receptors respectively). Displays selectivity for the δ₂ subtype in vivo.

Licensing Information

Sold with the permission of the University of Minnesota

Product Specifications for Naltriben mesylate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Naltriben mesylate

The following data is based on the product molecular weight 511.59.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 3 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.91 mL	19.55 mL	39.09 mL
2.5 mM	0.78 mL	3.91 mL	7.82 mL
5 mM	0.39 mL	1.95 mL	3.91 mL
25 mM	0.08 mL	0.39 mL	0.78 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Portoghese Role of spacer and address components in peptidomimetic δ opioid receptor antagonists related to naltrindole. J.Med.Chem. 1991 PMID: 1851846
• Thorat and Hammond Modulation of nociception by microinjection of delta-1 and delta-2 opioid receptor ligands in the ventromedial medulla of the rat. J.Pharmacol.Exp.Ther. 1997 PMID: 9399992
• Miyamoto Involvement of delta₂ opioid receptors in the development of mor. dependence in mice. J.Pharmacol.Exp.Ther. 1993 PMID: 8383738

Product Documents for Naltriben mesylate