Chemical Name: 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide
Biological ActivityNAN-190 hydrobromide is a 5-HT1A antagonist.
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Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat.
Arylpiperazine derivatives as high affinity 5-HT1A serotonin ligands.
Glennon et al.
NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).
Williams and Glennon
Citations for NAN-190 hydrobromide
The citations listed below are publications that use Tocris products. Selected citations for NAN-190 hydrobromide include:
3 Citations: Showing 1 - 3
Activity-dependent expression of Lmx1b regulates specification of serotonergic neurons modulating swimming behavior.
Authors: Demarque and
Gαo/i-stimulated proteosomal degradation of RGS20: a mechanism for temporal integration of Gs and Gi pathways.
Authors: Pagano Et al.
Physiol Behav 2008;20:1190
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Authors: Geerts Et al.
Br J Pharmacol 1999;127:1327
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