NAV 26

Catalog # Availability Size / Price Qty
4691/10
4691/50
Cat.No. 4691 - NAV 26 | C22H21F3N2O4 | CAS No. 1198160-14-3
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Description: Selective Nav1.7 channel blocker

Chemical Name: 2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide

Purity: ≥98%

Product Details
Reviews

Biological Activity

Selective Nav1.7 channel blocker (IC50 = 370 nM). Exhibits >85-fold selectivity for Nav1.7 over Nav1.5 and hERG channels. Reduces nociceptive behavior in rat models of pain.

Technical Data

M.Wt:
434.41
Formula:
C22H21F3N2O4
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1198160-14-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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