NCL 00017509

Catalog # Availability Size / Price Qty
NCL 00017509 | CAS No. 1507367-00-1 | Nek2 Kinase Inhibitors
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Description: Potent and reversible NIMA related kinase 2 (Nek2) inhibitor

Chemical Name: 3-[(6-Ethynyl-9H-purin-2-yl)amino]benzeneacetamide

Purity: ≥97%

Product Details
Citations (1)

Biological Activity

NCL 00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo. In mice bearing pancreatic tumors, NCL 00017509 decreases PD-L1 expression and induces an anticancer immune response.

Technical Data

Soluble to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for NCL 00017509

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