Nemonapride

Catalog # Availability Size / Price Qty
1746/10
1746/50
Nemonapride | CAS No. 75272-39-8 | Non-selective Dopamine Receptor Antagonists
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Description: Highly potent D2-like antagonist; also 5-HT1A agonist
Alternative Names: YM 09151, YM 09151-2

Chemical Name: cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide

Purity: ≥99%

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Biological Activity

Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.

Technical Data

M.Wt:
387.91
Formula:
C21H26ClN3O2
Solubility:
Soluble to 20 mM in ethanol and to 25 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
75272-39-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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