NFAT inhibitor, Cell Permeable

Catalog # Availability Size / Price Qty
5710/1
NFAT Inhibitors Peptide
1 Image
Description: Cell permeable NFAT inhibitor
Alternative Names: 11R-VIVIT
Product Details
Reviews (1)

Biological Activity

NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.

Technical Data

M.Wt:
3573.15
Formula:
C147H259N67O36S
Sequence:
RRRRRRRRRRRGGGMAGPHPVIVITGPHEE
Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
592517-80-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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To determine the effects of a cell permeable NFAT inhibitor in IC-21 cell line
By Meghan Bradshaw on 02/20/2019
Species: Human

NFAT function in macrophages and we worked to determine the effects of a cell permeable NFAT inhibitor in IC-21 cell line.


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