NGI 1

Catalog # Availability Size / Price Qty
6652/5
6652/25
Cat.No. 6652 - NGI 1 | C17H22N4O3S2 | CAS No. 790702-57-7
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Description: Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral

Chemical Name: 5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide

Purity: ≥98%

Product Details
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Biological Activity

Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral. Inhibits dengue, Zika, West Nile, and yellow fever viruses by blocking viral RNA replication (EC50 values are 0.85 and 2.2 μM for DENV and ZIKV inhibition, respectively). Selectively arrests proliferation of non-small-cell lung cancer cells that are dependent on EGFR or FGFR for survival.

Technical Data

M.Wt:
394.51
Formula:
C17H22N4O3S2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
790702-57-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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