Nicastrin Antibody Blocking Peptide

Name: Nicastrin Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NBP1-77269PEP
Price: 169 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-77269PEP

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

Synthetic

Applications

Antibody Competition

View all Nicastrin Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 17 amino acids near the carboxy terminus of human nicastrin.

Source: Synthetic

(Accession #: NP_056146)

Application Notes

This peptide is useful as a blocking peptide for NBP1-77269.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NBP1-77269PEP

Formulation	PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative	0.02% Sodium Azide
Concentration	0.2 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: Nicastrin

Nicastrin is a large protein that is a component of an enzyme called gamma-secretase, which is lodged in the cell's membrane. Nicastrin protein is physically associated with presenilin and plays an important role in stabilization and correct localization of presenilin to the membrane-bound gamma-secretase complex. Nicastrin also serves as a docking site for gamma-secretase substrates such as APP and Notch, directly binding to them and presenting them properly to gamma-secretase to ensure the correct cleavage process.

Alternate Names

APH2, NCSTN

Gene Symbol

NCSTN

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Product Documents for Nicastrin Antibody Blocking Peptide

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Product Specific Notices for Nicastrin Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.