NK1R Antibody Blocking Peptide

Novus Biologicals | Catalog # NB300-101PEP

Novus Biologicals
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Key Product Details

Applications

Antibody Competition
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Product Specifications

Description

A TACR1 antibody blocking peptide.

Application Notes

This peptide is useful as a blocking peptide for NB300-101. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB300-101 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB300-101PEP
Formulation Peptide dissolved in dH2O. Contains no BSA.
Preservative No Preservative
Concentration 1.0 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: NK1R

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Long Name

Neurokinin-1 Receptor

Alternate Names

SPR, TAC1R, TACR1

Gene Symbol

TACR1

Additional NK1R Products

Product Documents for NK1R Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for NK1R Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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