NKY 80

Key Product Details

Product Description

NKY 80 is an inhibitor of adenylyl cyclase (AC). Exhibits greater affinity for AC5 over AC3 and AC2 (IC₅₀ values are 8.3 μM, 132 μM and 1.7 mM respectively).

Product Specifications for NKY 80

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for NKY 80

The following data is based on the product molecular weight 229.23.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.36 mL	21.81 mL	43.62 mL
5 mM	0.87 mL	4.36 mL	8.72 mL
10 mM	0.44 mL	2.18 mL	4.36 mL
50 mM	0.09 mL	0.44 mL	0.87 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

• Pierre Capturing adenylyl cyclases as potential drug targets. Nat.Rev.Drug Discov. 2009 PMID: 19337273
• Onda Type-specific regulation regulation of adenylyl cyclase. Selective pharmacological stimulation and inhibition of adenylyl cyclase isoforms. J.Biol.Chem. 2001 PMID: 11602596

Product Documents for NKY 80