NNC 0640

Catalog # Availability Size / Price Qty
6807/50
6807/10
NNC 0640 | CAS No. 307986-98-7 | Glucagon-Like Peptide 1 Receptor Modulators
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Description: Negative allosteric modulator of glucagon and GLP-1 receptors

Chemical Name: 4-[[(4-Cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-ylbenzamide

Purity: ≥98%

Product Details
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Biological Activity

Negative allosteric modulator of glucagon receptors (pKi = 7.4). Binds to external surface of the transmembrane domain. Also negative allosteric modulator of glucagon-like peptide 1 (GLP-1) receptor. Inhibits GLP-1-mediated cAMP accumulation in vitro.

Technical Data

M.Wt:
573.67
Formula:
C29H31N7O4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
307986-98-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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