Highly selective T-type calcium channel blocker. Displays IC50
values of 6.8 and > 100 μ
M for inhibition of Cav
3.1 T-type channels and HVA currents respectively in INS-1 cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: A new selective inhibitor of T-type calcium cha
Huang et al.
CaV3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.
Chen et al.
The citations listed below are publications that use Tocris products. Selected citations for NNC 55-0396 dihydrochloride include:
Showing Results 1 - 5 of 5